
Microneedling With PRP and Exosomes vs Pylai Pen Alone
PRP and exosome add ons versus a straight Pylai Pen session, what you actually gain and what it costs.
Should You Add PRP or Exosomes or Just Use Pylai Pen?
Clinics love to upsell platelet-rich plasma (PRP) and exosomes on top of microneedling. Here is what those add ons really do, how they compare to a straight Pylai Pen session, and when to save or spend.
Quick Definitions
- PRP: Your own blood is spun to concentrate platelets, then applied while microchannels are open.
- Exosomes: Lab-grown vesicles loaded with growth factors; think of them as fancy signaling packets.
- Pylai Pen alone: Controlled channels plus a simple calming serum you already own.
Benefits Head to Head
- Texture and scars: Pylai Pen alone already boosts collagen. PRP can speed early healing; exosomes may add an extra nudge for stubborn scars.
- Redness and downtime: PRP often calms redness faster. Exosomes can feel soothing, but results vary by brand.
- Pigment-prone skin: Adding strong actives post-needling can backfire; a simple HA or centella serum is safest at home.
Cost Reality Check
- PRP session: You pay for blood draw, centrifuge, and clinic time—usually 1500–3500 RMB per visit.
- Exosome session: Premium pricing, often 2000–4000 RMB because of product cost.
- Home Pylai Pen: Fresh cartridge + gentle serum (under 50 RMB per session).
If your budget covers one big splurge, do a single clinic PRP session for scar-heavy zones, then maintain monthly with the Pylai Pen.
At-Home Alternatives That Still Help
- Use peptides or growth-factor-mimicking serums right after needling (fragrance-free).
- Stay at 0.25–0.5 mm for most face work; go shallower if you pigment easily.
- Space sessions 3–4 weeks; results stack over time.
When to Skip Add Ons
- Active acne, eczema, or any infection.
- On isotretinoin or recently had lasers/peels.
- If you are not strict with hygiene—focus on clean technique first.
PRP and exosomes can add a boost, but the core win still comes from consistent, sterile microneedling. Nail that routine before paying clinic-level pricing.

